I won't pretend to have done all the analysis, but this is likely one of the Vikings' easier games and they aren't going to be one of the stronger teams in the league, so I like the pick.
I'm going with a kind of personalized hybrid approach that involves some analytical data, Future Value, Expected Value, Ownership %, et al but puts a HIGH premium on the QB, with the HC as kind of a tiebreaker. I'm basically going to short, or go against the shit QBs, especially with shit HC's, all year, particularly ones with a high percentage chance to lose.
Buffalo and Detroit have the 4th and 5th highest chances/percentages to win in Week 1, 68% and 66%; but betting your season against Kyler Murray and/or Stafford/McVay respectively? No thanks.
Rookie QBs like Williams, Jayden Daniels and Nix scare me this early in the season, both good and bad. I'll stay away until I see more information. Everyone loves Seattle against Denver but Sean Payton with Nix, going against a new HC in Seattle and Geno Smith who was dinged up most of training camp? I can't go that route. I'm half-tempted to put a small bet on Denver to win on the M/L.
I like New Orleans and David Carr against Carolina in Week 1. Everyone's obvious pick is Cincinnati and if I'll pick them in 1 of my entries but only because I have multiple entries. I like the Chargers because the Raiders are shit, but not thrilled that SoFi will be more of a home game for the Raiders than it is the Chargers; the Raiders fans always fill that place.
Probably going with Saints, Bengals, and Vikings; and I've thought about ponying up for a 4th entry but not sure yet. With a 4th entry, I'd lean Chargers.