Well, if you're looking for hope, I was reading an article that ranked teams' minor league systems, and the person doing the rankings had the Twins' farm system ranked 5th.
There are some well-thought of pitching prospects - Winder, Canterino, Balazovich and Duran, to name a few starting prospects. and a reliever named Colina. Problem is that several have had injuries. Another high draft pick, Enlow, a starter, is out for the year after surgery.
Former top pick Royce Lewis is out this year with an injury, so he'll probably need some time in the minors, but he should be with the Twins at some point next year. The Miranda kid was tearing up AA, and they have moved him up to AAA, so he could be getting close. a 3B with power (replacement for Donaldson....?)
So, if the Twins can keep some of these guys healthy, they could potentially have a home-grown rotation in a couple of years.
But no doubt about it, Falvey and Levine have to make some better decisions on trades and free agents.