Yes, but as Slab of Bacon said above, if the running game is very effective, many defenses will start to bring a safety closer to the line of scrimmage (creating an 8 man box). This doesn't make our WRs or TEs any better at catching the ball, but it often makes the slant route more open for a moment or two, if the WR gets inside position on the CB or nickel back. When our RPO is working well, the QB's key is often what the run-side safety--who is put in a quandry--does immediately after the snap. If safety safety stays back, Morgan hands off; if safety moves down into the box, Morgan pulls the ball and throws. One of the reason Morgan has been so effective in our RPO offense, I think, is because he makes this read well.