Overall, I just don't see how hosting a game on Friday Regularly/Annually would be "good" for the U. It's a logistical nightmare to host a game on a Friday while school is in session.
Sure there is some benefit to being a standalone game, but lots of college football fans around the country are doing other things on Friday nights such as going to HS games. Baseball postseason is also going on during that time.
From the article, it won't be exclusively Big 10 games on Friday night, but also Big 12 and the Mountain West.
Once every 3 years would be plenty fine. 4 or 5 would be even better and more than enough in my book.